"Doctors, patients and researchers are looking for alternative treatments for triple negative breast cancer, and people are always looking for ways to prevent cancer," said Patrick Martin, Ph.D., associate professor at North Carolina Agricultural and Technical State University and leader of the study. "How awesome would it be to be able to say: Here, take a daily vitamin tablet from the rose plant to possibly help prevent or treat cancer? It's a natural product that we found to be effective, with no known side effects."

Triple negative breast cancer draws its name from the fact that the cancer cells in these tumors lack the three growth factor receptors that are normally targeted during breast cancer treatment. As a result, most existing treatments are ineffective against it, and triple negative breast cancer patients who do go into remission experience higher recurrence and death rates in the first three years compared with other types of breast cancer.

In the study, the scientists treated tissue cultures of triple negative breast cancer cells with several concentrations of rosehip extract. Exposure to the highest concentration (1.0 mg/ml) decreased triple negative breast cancer cell proliferation by 50 percent. The effect was reduced with decreasing concentrations. The highest concentrations of rosehip extracts (.025 to 1.0 mg/ml) decreased triple negative breast cancer cell migration by 25 to 45 percent. Additional experiments revealed that the extract appears to work by reducing MAPK and Akt, two enzymes that are known to promote cell growth in triple negative breast cancer.

The extract also enhanced the ability of the commonly used breast cancer chemotherapy drug doxorubicin to decrease cell proliferation and migration in the tissue cultures, suggesting rosehip extract might be a beneficial addition to the overall treatment regimen for patients with triple negative breast cancer.

"My hope is that our studies in tissue cultures, along with future studies in animal models, will lead to rosehip being recommended as a preventive measure in breast cancer or as an addition to current cancer treatment," Martin said.

Patrice Cagle, a doctoral student in Martin's lab, said she feels a personal connection to the research. "I am a young African-American female so there's a higher risk for me to potentially get triple negative breast cancer," she said. "There isn't a lot of research on triple negative breast cancer and African-Americans, so we're trying to increase the profile of this particular cancer in the scientific community and in the public eye." Cagle will present this research at the American Society for Pharmacology and Experimental Therapeutics (ASPET) Annual Meeting during Experimental Biology 2015.

The outlook for African-American women with triple negative breast cancer is particularly poor, an aspect Cagle said should be investigated further. Scientists speculate the disparity might be tied to biologic and genetic differences, prevalence of risk factors, barriers to health care access, health behaviors or the fact that African-American patients tend to be diagnosed with breast cancer at a later stage of the disease.

Rosehips, the round part of the rose flower located just below the petals, are used as a natural source of vitamin C in tea and other foods. For the experiments, the researchers used pure rosehip, which can be purchased as a supplement in pill or liquid form.

The breast cancer research grew out of previous studies in which the investigators used rosehip extract to successfully prevent cancer cell growth in the brain, one of the places to which triple negative breast cancer tends to spread. They would also like to test the extract's effects on prostate cancer cells.

To receive daily emails from Breaking Christian News to your inbox CLICK HERE

'The Chosen' Finds a New Home on Streaming Platform: 'A Tremendous Win for Disney's Image'

The Homeschooling Miracle in the Pacific Northwest: 'Nothing Is Impossible for God'

Arizona Republican Party Declares Covid-19 Injections Biological and Technological Weapons, Passes 'Ban the Jab' Resolution!

Biden Swamped by Lawsuits Minutes after Upending Title IX

Judge Relents, Rules Trump Can Attend Son Barron's Graduation

'Utter Chaos' at UCLA as Pro-Israel Vigilantes Storm Palestine 'Encampment' Overnight [Videos]

'Hamas and Supporters Are Not Welcome on Native Land!'; Native Americans Come Out in Force, Confront Anti-Israel Mob at UCLA

'Outside Agitators': NYPD Releases Video Showing Professional 'Protest Consultant' at Columbia University

Australia Calls For 3 Days Prayer & Fasting for America, April 30 - May 2nd

Arabella Network's Leftist 'Dark Money' Influence Expanding, Author Reveals

CA Bill to Inform Teens About Pregnancy Care Centers Voted Down by Legislators

Unbelievable: Jailed Pro-Lifer Says She Was Kept in Solitary Confinement for 22 Days With Lights on 24/7

The Rise of Islamism in America; How We Can Be Praying

Israel at Crossroads Between Rafah Incursion, Hostage Deal as Blinken Visits

Antisemites Barricade Themselves in Columbia's Hamilton Hall Overnight as Tensions Skyrocket

Judge Merchan Holds Donald Trump in Criminal Contempt for Gag Order Violations, Threatens Jail Time

Prayer & Action Alert: 5 Dead after 130 Tornadoes Rip through America's Heartland; Ministries Helping to Rebuild

Tennessee Passes 'Baby Olivia Act' Requiring Public Schools Show Development of Unborn Babies

Soros-Backed LA DA George Gascon's Top Adviser Charged With 11 Felonies: Report

TX Rep. Chip Roy Raises Alarm About George Soros' Purchase of 2nd Largest Radio Co. in the US