...Is Apeel Part of ...Biden's GMO Agenda?

One of the first things that came to mind when I heard of Apeel is that it fits right into ...Biden's recently launched agenda to turn the US food supply over to the biotechnology industry. I reviewed this agenda in "Executive Order Lays Foundation for Lab-Created Foods."

In summary, Biden's September 2022 "Executive Order on Advancing Biotechnology and Biomanufacturing Innovation for a Sustainable, Safe and Secure American Bioeconomy"17 makes biotechnology a national priority across agencies and branches of government, including the US Department of Agriculture (USDA).

In late March 2023, Biden expanded on this premise in a "Bold Goals for US Biotechnology and Biomanufacturing" report.18 One of the specific goals listed in this report is "Reducing food waste by 50% by 2030." Reducing food waste to combat climate change19 is also the premise upon which Apeel Sciences was founded, according to its website.20.

Further evidence that Apeel Sciences fits into Biden's biotech-driven food agenda is its acquisition of ImpactVision, "a software company that uses AI and machine learning to track the chemical composition of food throughout its shelf life."21 The company has also promised to "double down on technology" through other tech acquisitions.

While reducing food waste and making fresh produce last longer are certainly sane and worthy goals, the question is, how is this being done? Seeing how Apeel's emergence broadly coincides with Biden's official transition into biotech-led foods, can we trust that it's a food-based product? Or is it biotech in disguise?

What Does Apeel's GRAS Notice Tell Us?

According to Apeel Sciences:

"Apeel adds a little extra peel on produce to slow the rate of water loss and oxidation ... That extra peel is completely edible, tasteless and safe to eat. A variety of plant feedstocks can be used to create our formulations, and luckily these ingredients exist in the peels, seeds and pulp of all fruits and vegetables ...

We think of these materials as building blocks, restructuring them in a way that allows us to iterate on what nature created, making our solution into a coating that can be applied to produce. So while nature is our foundation and inspiration, innovation and technology are how we apply these ingredients ..."

Apeel Sciences' Generally Recognized as Safe (GRAS) notice22 to the US Food and Drug Administration, submitted in October 2019, gives us a little more. The primary component of the coating is said to be a mixture of monoacylglycerides derived from grapeseed.

An earlier GRAS Notice,23 filed in April 2016, further specifies that the two primary components of Apeel is 2,3-dihydroxypropyl palmitate and 1,3-dihydroxypropan-2-yl palmitate. (In this notice, the product is called "Edipeel," but the website now refers to it as "Apeel," like the company name.) According to the 2016 GRAS Notice No. 648:

"Monoacylglycerol derivatives are components of dietary fats commonly found in food and are also endogenously formed in the human body ... It is well established and recognized that monoacylglycerides, the subject of the present GRAS assessment, are formed in the gastrointestinal tract from the generally accepted metabolic pathway for the breakdown of triglycerides (i.e., lipolysis).

The hydrolysis of triglycerides by lipases proceeds through the formation of monoacylglycerides (i.e., monoglycerides). The free fatty acids released can be further used for triglyceride synthesis.

Given the metabolic sequel described above, and by applying scientific procedures, it can be concluded that a mixture of monoacylglycerides would not pose any health hazards different from commonly consumed dietary oils derived from plants or animals."

Toxic Residues

However, just because something is made from all-natural ingredients doesn't mean the final product is perfectly safe. It depends on what you've done to those ingredients.

In this case, in Part 3 of the 2019 GRAS notice,24 under Maximum Limit of Residues, we find that the grape seed oil that makes up the basis of this product contains residues of ethyl acetate, heptane and palladium, which are processing aids, as well as the heavy metals arsenic, lead, cadmium and mercury.

According to Apeel, the levels of these toxic residues are either below levels deemed safe by the FDA, the EU and/or the Joint FAO/World Health Organization Expert Committee on Food Additives (JECFA). The following table lists the maximum daily exposure limits based on a maximum daily (90th percentile) intake of 218 milligrams per person per day.

Maximum daily exposure limits

While the levels indeed appear to be very low, I would argue that any exposure to toxic chemicals and metals is an unnecessary risk. To me, intentionally coating fresh, unadulterated foods with something that contains toxins, even if in minute amounts, only adds to the toxic burden. We're already dealing with pesticide residues on conventional fruits and vegetables. This coating will simply lock those toxins in and add additional ones on top.

One of the biggest question marks is whether this coating can penetrate the peel, as the coating cannot be washed off. Can toxic risks be eliminated by peeling the produce, or is the flesh of the fruit or vegetable also contaminated with residues? We do not have the answer to that question, even though it's one of the most important ones.

According to Apeel Sciences, the coating is "not expected" to penetrate beyond the peel into the fruit.25. Not expected? That means they have no idea. They're simply guessing.

More Open Questions

In Apeel Sciences' 2019 GRAS notice, they referenced a 2017 EFSA review26 of E471 (mono- and diglycerides of fatty acids) but didn't mention that this review warned about the possible presence of epichlorohydrin,27 a carcinogen, in E471 manufactured using glycerol or glycidol as a starting material. Apeel uses monoglycerides of glycerol.

According to this review, "The panel considered that the presence of epichlorohydrin and/or glycidol in mono- and di-glycerides of fatty acids (E 471) would need further assessment as their presence could raise a safety concern." Palladium, cadmium and arsenic are also carcinogenic, so there are at least four different carcinogenic contaminants in this coating.

What's more, a 2021 European Food Safety Authority (EFSA) re-review28 of monoacylglycerides found that "the potential exposure to toxic elements resulting from the consumption of E 471 could be substantial." As a result, the review panel suggests it may be necessary to lower existing limits for arsenic, lead, cadmium and mercury.

Apeel Plans to Switch to Synthetic Biology

Baden-Mayer also wonders whether Apeel's coating is made with synthetic biology. Why else is Apeel Sciences listed as one of the best-funded synbio companies?29. Don't you have to produce synthetic biology products to be considered a synbio company?

In 2018, the Apeel founder himself also told Food Navigator that his company would soon transition to using synthetic biology rather than extracting its ingredients from real food.30. So, even if they haven't made that transition yet, this certainly suggests they intend to, eventually.

Apeel's GRAS notice also leaves this door open, stating that "monoacylglycerides can be created by breaking down a triglyceride by removing two of its fatty acids or they can be manufactured synthetically."

Finally, Apeel Sciences' board of directors includes Vijay Pande,31,32 an adjunct professor of bioengineering at Stanford, who also serves on the board of Scribe Therapeutics, a company specializing in CRISPR technology and protein engineering. Pande is also the founder of Globavir Biosciences, an infectious disease start-up.

So, it certainly appears as though Apeel Sciences is geared up to move into genetically engineered synthetic biology, if they haven't made that leap already. The company is even directly connected to a company specializing in infectious disease therapeutics, and we now know there are efforts underway to turn foods into vaccine vectors... Subscribe for free to Breaking Christian News here

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