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Blood Test Promises to Find Single Cancer Cell Among Millions of Normal Ones"There's a lot of potential here, and that's why there's a lot of excitement." (Raritan, NJ)—Several news agencies this week have reported on an AP story about a "revolutionary" blood test that can spot a single cancer cell among millions of healthy ones. Since four large cancer centers will be using it in studies, and Johnson & Johnson has decided to bring it to the market, it signals great hope for early detection of the disease. "Measuring CTCs in metastatic breast cancer patients provides oncologists with an additional tool to help us better monitor patient outcomes," said one of the lead authors, Dr. Massimo Cristofanilli, associate professor in the Department of Breast Medical Oncology at The University of Texas M. D. Anderson Cancer Center. "The CellSearch(R) CTC test provides an early indication about patients' disease progression and overall survival." The CellSearch(R) test works by using antibodies that are joined to microscopic iron particles, called ferrofluid. These antibody/ferrofluid combinations attach very specifically to CTCs. Powerful magnets then draw the CTCs out of the blood sample and they are then stained with additional bio-molecules and chemicals so that they can be positively identified as CTCs.
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