|
To receive daily emails from Breaking Christian News to your inbox CLICK HERE
Grape Seed Extract Kills Laboratory Leukemia Cells, Proving Value of Natural Compounds"What everyone seeks is an agent that has an effect on cancer cells but leaves normal cells alone, and this shows that grape seed extract fits into this category."
The investigators, who report their findings in the January 1, 2009, issue of Clinical Cancer Research, a journal of the American Association for Cancer Research, also teased apart the cell signaling pathway associated with use of grape seed extract that led to cell death, or apoptosis. They found that the extract activates JNK, a protein that regulates the apoptotic pathway. While grape seed extract has shown activity in a number of laboratory cancer cell lines, including skin, breast, colon, lung, stomach and prostate cancers, no one had tested the extract in hematological cancers nor had the precise mechanism for activity been revealed. "These results could have implications for the incorporation of agents such as grape seed extract into prevention or treatment of hematological malignancies and possibly other cancers," said the study's lead author, Xianglin Shi, Ph.D., professor in the Graduate Center for Toxicology at the University of Kentucky. "What everyone seeks is an agent that has an effect on cancer cells but leaves normal cells alone, and this shows that grape seed extract fits into this category," he said. Shi adds, however, that the research is not far enough along to suggest that people should eat grapes, grape seeds, or grape skin in excess to stave off cancer. "This is very promising research, but it is too early to say this is chemo-protective." Hematological cancers—leukemia, lymphoma and myeloma—accounted for an estimated 118,310 new cancer cases and almost 54,000 deaths in 2006, ranking these cancers as the fourth leading cause of cancer incidence and death in the U.S. Given that epidemiological evidence shows that eating vegetables and fruits helps prevent cancer development, Shi and his colleagues have been studying chemicals known as proanthocyanidins in fruits that contribute to this effect. Shi has found that apple peel extract contains these flavonoids, which have antioxidant activity, and which cause apoptosis in several cancer cell lines but not in normal cells. Based on those studies, and findings from other researchers that grape seed extract reduces breast tumors in rats and skin tumors in mice, they looked at the effect of the compound in leukemia cells. Using a commercially available grape seed extract, Shi exposed leukemia cells to the extract in different doses and found the marked effect in causing apoptosis in these cells at one of the higher doses. They also discovered that the extract does not affect normal cells, although they don't know why. "This is a natural compound that appears to have relatively important properties," Shi said. 
To receive daily emails from Breaking Christian News to your inbox CLICK HERE
Other Recent Articles from Breaking Christian News Atheists Triggered by Billy Graham Statue in the US Capitol More Shady Biden Accounts Have Been Discovered House Judiciary Votes to Hold AG Merrick Garland in Contempt of Congress Fed Court: Parents in Maryland School District CANNOT Opt K-5 Children Out of LGBTQ Curriculum 'For Love of Country': Tulsi Gabbard Is Free from the Democrat Party She No Longer Recognizes Soros-Linked DC Judge Releases Teen Gunman after He Sprayed Dozens of Shots at a Car Kansas City Chiefs Kicker Slams Biden for Supporting Abortion in College Commencement Speech Persecution of Pro-Life Americans Continues With This Week's Sentences in DC FACE Act Case Senator Paul to Newsmax: Scientist Affirms Gain-of-Function in Wuhan, 'This Is a Really Big Deal' Canada's Intelligence Agency Classifies Opponents of LGBT Gender Ideology as a 'Violent Threat' Argentina's Javier Milei Is Proving the Leftists Wrong With Latest Economic News As Memorial, Independence Days End, Israel's Attention Turns to Rafah, Hezbollah Battlefronts New Biden Rule Aims to Entrench the Deep State Forever |
    
  |
An extract from grape seeds forces laboratory leukemia cells to commit cell suicide, according to researchers from the University of Kentucky. They found that within 24 hours, 76 percent of leukemia cells had died after being exposed to the extract. 
All articles on this site and emails from BCN are copyrighted property of Breaking Christian News. Permission is given to link to, or share a BCN story if proper attribution is given to both the original writer and summarizer of the story. Breaking Christian News 2005-2019. All Rights Reserved.
Breaking Christian News is a division of Elijah List Publications, Inc. All Rights Reserved
Disclaimer: Articles and links, as well as the source articles linked to; do not necessarily reflect the opinion of Breaking Christian News.
| Home | Store | Subscribe | Facebook | Article Archive |