They say the results advance the hope that supplementing with broccoli sprout extract, which contains high levels of the chemical sulforaphane, may someday provide a way to lower the doses of traditional antipsychotic medicines needed to manage schizophrenia symptoms, thus reducing unwanted side effects of the medicines.

"It's possible that future studies could show sulforaphane to be a safe supplement to give people at risk of developing schizophrenia as a way to prevent, delay or blunt the onset of symptoms," adds Akira Sawa, MD, Ph.D., professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine and director of the Johns Hopkins Schizophrenia Center.

Schizophrenia is marked by hallucinations, delusions and disordered thinking, feeling, behavior, perception and speaking. Drugs used to treat schizophrenia don't work completely for everyone, and they can cause a variety of undesirable side effects, including metabolic problems increasing cardiovascular risk, involuntary movements, restlessness, stiffness and "the shakes."

In a study described in the Jan. 9 edition of the journal JAMA Psychiatry, the researchers looked for differences in brain metabolism between people with schizophrenia and healthy controls. They recruited 81 people from the Johns Hopkins Schizophrenia Center within 24 months of their first psychosis episode, which can be a characteristic symptom of schizophrenia, as well as 91 healthy controls from the community. The participants were an average of 22 years old, and 58% were men.

The researchers used a powerful magnet to measure and compare five regions in the brain between the people with and without psychosis. A computer analysis of 7-Tesla magnetic resonance spectroscopy (MRS) data identified individual chemical metabolites and their quantities.

The researchers found on average 4% significantly lower levels of the brain chemical glutamate in the anterior cingulate cortex region of the brain in people with psychosis compared to healthy people.

Glutamate is known for its role in sending messages between brain cells, and has been linked to depression and schizophrenia, so these findings added to evidence that glutamate levels have a role in schizophrenia...

The scientists say further research is needed to learn whether sulforaphane can safely reduce symptoms of psychosis or hallucinations in people with schizophrenia. They would need to determine an optimal dose and see how long people must take it to observe an effect. The researchers caution that their studies don't justify or demonstrate the value of using commercially available sulforaphane supplements to treat or prevent schizophrenia, and patients should consult their physicians before trying any kind of over-the-counter supplement. Versions of sulforaphane supplementsare sold in health food stores and at vitamin counters, and aren't regulated by the US Food and Drug Administration.

"For people predisposed to heart disease, we know that changes in diet and exercise can help stave off the disease, but there isn't anything like that for severe mental disorders yet," says Sedlak. "We are hoping that we will one day make some mental illness preventable to a certain extent."

Sulforaphane is found in a variety of cruciferous vegetables, and was first identified as a "chemoprotective" substance decades ago by Paul Talalay and Jed Fahey at Johns Hopkins.

According to the World Health Organization, schizophrenia affects about 21 million people worldwide. Subscribe for free to Breaking Christian News here

To receive daily emails from Breaking Christian News to your inbox CLICK HERE

Hundreds Accept Jesus Christ in Poland at Franklin Graham Rally

Grammy-Winning Christian Artist Mandisa Has Died: Report

How You Can Send Letters of Encouragement to Jailed Pro-Life Heroes

'Americans Cannot Allow the Biden Administration to Sign Away Their Birthright': Congressmen Warn of WHO Pandemic Agreement

Illegal Immigrants Being Moved into Soldiers' Home Where Veterans Must Pay to Stay

House Democrats Vow to Codify 'Rights' to Trans Surgeries, Hormones, Puberty Blockers

18-Year-Old Female Trans Student Charged for Planning Two Maryland School Shootings, Manifesto Said She Wanted to Be 'Famous'

Israel Strikes Deep Inside Iran, Nuclear Facilities NOT Hit

An Important Message from Japan to the world about the WHO, Japan and the Next So-called 'Vaccine'

Rand Paul: Brave Marine Revealed that 15 US Agencies Knew COVID-19 Was Created in Lab in 2018; But They Kept It Secret from American Public (VIDEO)

Confirmed: Researchers Reveal COVID mRNA Vaccines Contain Component that Suppresses Immune Response and Stimulates Cancer Growth

Farmers, Truckers Warn California Emissions Mandates Will Cause 'Catastrophic' Supply Chain Crisis

Fed Court Overturns State Law Protecting Women's Sports from 'Transgender' Athletes

Furry Infestation: Middle School Students Walk Out in Protest after School Leaders Allow 'Furries' to Terrorize Them (VIDEO)

Biden's Education Secretary Vows to Shut Down the Largest Christian University in the US

US to Back Rafah Op in Exchange for Israel Dropping Major Iran Strike; Report

Schumer Succeeds in Killing Off Mayorkas Impeachment Trial before It Can Even Begin

California Town Tears Down Beloved Hillside Cross

Danielle Smith Again Defends Alberta's Coming Ban on Transgender Mutilation of Children

Detransitioners: We Were Pushed to Transition as Teens, Now We're 'Vindicated' By Study Showing Kids Grow Out of It