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7 Proven Black Seed Oil Benefits & Cures

Dr. Josh Axe : Apr 18, 2017 : Food is Medicine

With virtually no side effects, the healing prowess of black seed is actually quite unbelievable and it boggles the mind that most Americans have never heard of it!

[Food is Medicine] Of the 630 scientific peer-reviewed articles that have been published about black seed oil benefits, one fact is clear: there are few issues that it cannot help the body overcome. With virtually no side effects, the healing prowess of black seed is actually quite unbelievable and it boggles the mind that most Americans have never heard of it! (Photo Credit: Dr. Josh Axe/ Food is Medicine)

Unique Black Seed Oil Benefits

The uniqueness of the seeds from southwest Asia Nigella sativa is first realized by the many names that it is referred to: (1)

  • Black cumin
  • Black caraway
  • Black sesame
  • Onion seed
  • Roman coriander 

"Black seed" is actually more of a description than a proper name, yet is preferred because it helps to distinguish it from caraway and cumin. Many health experts claim that it is, indeed, a true panacea; able to help cure everything from allergies to hypertension. Quite possibly, the most promising research has been done connecting Nigella sativa to multi-drug resistant bacteria. This is a real big deal because these so-called "superbugs" are becoming a significant public health risk. According to the National Institute of Health: (2)

  • Strains of bacteria and viruses that are antimicrobial-resistant are becoming virtually impossible to treat; including HIV, staphylococcal, tuberculosis, influenza, gonorrhea, candida, and malaria.
  • Between 5 – 10% of all hospital patients develop an infection from superbugs.
  • More than 90,000 of these patients die every year, up from 13,300 patient deaths in 1992.
  • People infected with superbugs typically have longer hospital stays, require more complicated treatment and don’t recover as well.

A study conducted by Jawaharlal Nehru Medical College researchers set out to determine just how potent black seed oil against some of these superbugs and pared it against several antibiotics such as Amoxicillin, Gatifloxacin and Tetracycline. According to the study, (Photo Credit: Dr. Josh Axe/ Food is Medicine)

"Out of 144 strains tested, most of which were resistant to a number of antibiotics, 97 were inhibited by the oil of black cumin!"

Next to oil of oregano, few things on the planet can boast this type of potency to microbes! The study uncovered that it was especially effective against multidrug resistant strains of P. aeruginosa and S. aureus.

The key to understanding why black seed oils benefits the body in this way is because it is rich in 3 key natural chemicals: thymoquinone (TQ), thymohydroquinone (THQ) and thymol.

The Power Behind Black Seed Oil Benefits: Phytochemicals

In an effort to offer a solution to the growing antifungal resistant problem people have with yeasts and molds, a recent study was conducted with the purpose of determining if Nigella sativa seed oil could help. Published in the Egyptian Journal of Biochemistry & Molecular Biology, scientists tested thymol, TQ and THQ against 30 human pathogens and were surprised to discover that: (3) (Photo Credit: Dr. Josh Axe/ Food is Medicine)

  • Each compound showed 100% inhibition for the thirty pathogens evaluated.
  • Thymoquinone was the best antifungal compound against all of the tested dermatophytes and yeasts, followed by thymohydroquinone and thymol.
  • Thymol was the best antifungal against molds followed by TQ and THQ.

What this study tells us is that Nigella sativa oil carries a very unique chemical constituency that is not only effective individually, but more importantly also collectively. Essentially proving that fungus and molds cannot exist in the presence of these phytochemicals, it is no wonder why researchers are seeking to solve the superbug problem with the mighty black seed!

Thymoquinone – An active ingredient in black seed, researchers have been investigating TQ since the 1960s. It is well known for its anti-oxidant, anti-inflammatory and anticancer properties that have been reported to help with encephalomyelitis, diabetes, asthma and carcinogenesis. (4) Interestingly, thymoquinone acts as a free radical or an effective superoxide radical scavenger, in addition to preserving antioxidant enzymes glutathione peroxidase and glutathione-S-transferase. Both Glutathione peroxidase and S-transferase are heralded for being major detoxifiers and greatly aid in cellular antioxidant defense systems because they protect the liver from toxins. (4,5)

Thymohydroquinone – A kin to thymoqinone, thymohydroquinone is one of the most potent natural acetylcholinesterase (AChE) inhibitors on the planet. (6) AChE inhibitors are chemicals that stop enzyme activity, which increases the amount of time and the amount of the neurotransmitter acetylecholine remains active in the brain. To give you an idea of their usefulness, pharmaceutical-grade acetylcholinesterase inhibitors are used medicinally to treat a wide range of conditions including: (7)

  • Apathy
  • Alzheimer’s disease
  • Autism
  • Glaucoma
  • Dementia
  • Myasthenia gravis
  • Neurodegenerative conditions
  • Postural Tachycardia Syndrome
  • Schizophrenia
  • Parkinson’s disease

Considering that the pharmaceutical approach to these diseases comes at a great cost to the patient, it offers much hope to literally millions to learn that safe, plant-based solutions are a viable alternative!

Thymol – The active ingredient that gives thyme essential oil its medicinal properties, thymol is a natural monoterpene that holds a number of useful qualities. For example, (8) (9)

  • It is commonly used as a tuberculocide and virucides to kill TB and various viruses.
  • It is used as a medical and general-purpose disinfectant.
  • It is a rapidly degrading, non-persisting pesticide.
  • It is also used in food flavorings, perfumes, mouthwashes, and even cosmetics.

According to the Environmental Protection Agency (9)

Thymol is among those pesticides for which EPA believes a broadly reduced set of generic data requirements is appropriate for reregistration. The Agency, therefore, has waived most generic data requirements for thymol with the exception of studies that are considered essential, including additional information about chemical purity, and product chemistry studies.

Top 7 Black Seed Oil Benefits

Of the many ways that black seed oil benefits the body, the 6 that stick out in the scientific literature its ability to help prevent cancer, diabetes, obesity, hair loss, skin disorders and infections like MRSA.

1. Cancer

Croatian scientists evaluated the antitumor activity of thymoquinone and thymohydroquinone in mice and discovered that the two phytochemicals in black seed oil can resulted in 52% decrease in tumor cells! (10) (Photo Credit: Dr. Josh Axe/ Food is Medicine)

Being rich in both chemicals, black seed is unique in that it can help prevent and treat cancer through a variety of mechanisms:

  • Anti-proliferation
  • Apoptosis induction
  • Cell cycle arrest
  • Reactive oxygen species generation
  • Anti-metastasis
  • Anti-angiogenesis

According to one study,

"The anti-tumor effects of thymoquinone have also been investigated in tumor xenograft mice models for colon, prostate, pancreatic and lung cancer. The combination of thymoquinone and conventional chemotherapeutic drugs could produce greater therapeutic effect as well as reduce the toxicity of the latter." (11)

2. Liver Health

The liver is one of the most important organs in the body. Nearly every toxin gets processed through the liver, and the bile from the liver is the key to digesting fats and keeping your mind and body happy and healthy. For those that have struggled with poor liver function due to medication side effects, alcohol consumption, or disease, black seed oil could greatly speed the healing process. In a recent study scientists discovered that black seed oil benefits the function of the liver and helps prevent both damage and disease. (12)

3. Diabetes

Explained in a recent article published by the Journal of Endocrinology and Metabolism, researchers from the Indian Council of Medical Research highlight that black seed oil "causes gradual partial regeneration of pancreatic beta-cells, increases the lowered serum insulin concentrations and decreases the elevated serum glucose." (13) This is actually quite profound because Nigella sativa is one of the few substances on the planet that is suggested to help prevent both type 1 and type 2 diabetes. (Photo Credit: Dr. Josh Axe/ Food is Medicine)

In fact, according to the study, black seed "improves glucose tolerance as efficiently as metformin; yet it has not shown significant adverse effects and has very low toxicity!" (13) This is HUGE because metformin, one of the most commonly prescribed type 2 diabetes drugs, can cause a wide slew of side effects including: (14)

  • Bloating
  • Constipation/Diarrhea
  • Flushing of the skin
  • Gas/Indigestion
  • Heartburn
  • Headache
  • Nail changes
  • Metallic taste in mouth
  • Muscle pain
  • Stomach pain

4. Weight Loss

The Journal of Diabetes and Metabolic Disorders published a study last June systemically reviewing the literature for plants that have anti-obesity properties and discovered that black seed oil was amongst the most effective natural remedies on the planet. (15)

Not traditionally believed to treat obesity, Nigella sativa is a marvelous anti-inflammatory agent that is known to help people lose weight in the same way that it helps diabetics. Specifically, by decreasing these weight gain triggers, black seed oil has helped millions shed excess weight: (16)

  • Appetite
  • Glucose absorption in the intestine
  • Liver gluconeogenesis
  • Blood glucose levels
  • Cholesterol
  • Triglycerides

5. Hair

Probably one of the most unique black seed oil benefits is its uncanny ability to help restore hair loss. No one quite understands why it happens, but it’s not too hard to guess that it has something to do with its powerful antioxidant and antimicrobial properties. By strengthening hair follicles, there is very good reason to see how black seed oil can help promote strengthened hair roots.

6. Skin

Produced in the retina, choroid and epidermis, melanins are pigments that protect the skin from damage. You probably are most family with it being the main chemical responsible for giving our eyes and skin their individual color. Known to promote and inhibit melanogenesis (melanin production), black seed oil benefits on the skin and other cells are profoundly healing. (17, 18)

For example, in a recent study conducted by Iranian researchers, Nigella saliva was found as effective as the skin cream Betamethasone in improving quality of life and decreasing severity of hand eczema. (19) When you consider that black seed oil has virtually no side effects, the benefits of Nigella, in fact, far exceed medical intervention!

7. Infections (MRSA)

Of all the superbugs that black seed oil can kill, Methicillin resistant Staphylococcus aureus (MRSA) is one of the most important. MRSA is plaguing hospitals and nursing homes across the globe because ordinary staph infections are becoming resistant to generic antibiotics. The elderly population is especially at risk because it is generally associated with invasive procedures such as surgeries, intravenous tubing, and artificial joints. (20) Primarily due to weakened immunity, the growing population of senior citizens has made MRSA a global public health risk.

Thankfully, one of the strongest black seed oil benefits comes to the rescue.  Pakistan scientists took several strains of MRSA and discovered that each one was sensitive to N. Sativa, proving that black seed oil can help slow down or stop MRSA from spreading out of control. (21)

Final Note:

With all of these health benefits, I cannot think of one reason why everyone on the planet shouldn’t have black seed oil in their medicine cabinets!

Food is Medicine







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