There are multiple, serious, health risks associated with using the birth control pill and combined hormone replacement therapy (CHRT), both of which contain estrogen and progestin, although the former contains a larger dose. The authors of both reviews urged physicians to warn patients about the harms of taking either these drugs.

Schneider's team said, "...having more than one risk factor compounds the risk of breast cancer via synergistic mechanisms," meaning the risk increase the woman incurs is greater than the sum of the risks for each of her risk factors. They explained:

"The strength of the breast cancer epidemiological evidence substantiates the necessity that all females receive full and accurate informed consent before they are provided hormones, induced abortion, or both. This informed consent is especially imperative for a girl (and parent/guardian) or a young woman, who is in the pre-FFTP breast cancer 'susceptibility window.' As a family history of breast cancer, of which the child may be unaware, increases the risk for the girl considering an abortion, the presence of a parent may provide clinical information critical to accurate informed consent."

Karen Malec, president of the Coalition on Abortion/Breast Cancer, explained:

"The 'susceptibility window' is the period between the onset of menstruation and first full term pregnancy (FFTP) when nearly all of the breast lobules are immature and cancer-susceptible. The worst time to be exposed to a cancer-causing agent is during the susceptibility window."

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