Teresa Neumann : Aug 14, 2012 : Emma Little – The Sun

Researchers call results "astounding."

(Minneapolis, MN)—A report in The Sun reveals that researchers found a pill containing a chemical called NIC5-15 found in Pine cones and bark can slow the progression of Alzheimer's.

Calling the results "astounding," the report went on to say that human trials are underway to determine safety and if approved it would be a "huge step forward" in stopping the dreaded disease.

A press release from Humanetics Corporation, the company researching the drug, says: US Patent and Trademark Office has issued a patent supporting a long-term, multi-year research and development collaboration between Mount Sinai School of Medicine (MSSM) and Humanetics Corporation to develop and commercialize a safe and effective means to prevent or slow the progression of Alzheimer's disease. Humanetics is the exclusive licensee for this patent.

In collaboration with MSSM, Humanetics is developing the use of NIC5-15 to slow the progression of Alzheimer's disease. This compound, currently in a Phase IIb trial in the New York area, has been shown in preclinical studies and animal models to be effective in preventing the formation of beta-amyloid plaques, which are believed to be a leading cause of Alzheimer's disease. A Phase IIa study was completed at the Mount Sinai Alzheimer's Disease Research Center in 2008.

An estimated 4.5 million Americans have Alzheimer's disease and 18 million are afflicted worldwide. The market in the U.S. for drugs to treat Alzheimer's disease is estimated to be $2 billion, with the worldwide market in excess of $4 billion. Thus far, there are no drugs approved for use that can prevent or reduce amyloid plaques.

"We are pleased that NIC5-15 has reached this critical milestone," said Ronald Zenk, President and CEO of Humanetics. "There is an urgent need for safe and effective disease modifying agents to lessen the debilitating symptoms of Alzheimer's disease. We are hopeful that NIC5-15 will satisfy that need."

   

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